6WGH
Crystal structure of GDP-bound NRAS with ten residues long internal tandem duplication in the switch II region
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GTPase NRas | polymer | 181 | 20521.2 | 2 | UniProt (P01111) Pfam (PF00071) | Homo sapiens (Human) | Transforming protein N-Ras |
| 2 | C, G, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 3 | D, I (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 4 | E (A) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 5 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 180 (UniProt: P01111)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Glu 63 | - | insertion |
| Tyr 64 | - | insertion |
| Ile 65 | - | insertion |
| Leu 66 | - | insertion |
| Asp 67 | - | insertion |
| Thr 68 | - | insertion |
| Ala 69 | - | insertion |
| Gly 70 | - | insertion |
| Gln 71 | - | insertion |
| Glu 72 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41042.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1240.5 | |
| All* | Total formula weight | 42282.9 |
