6WBN
Cryo-EM structure of human Pannexin 1 channel N255A mutant, gap junction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Pannexin-1 | polymer | 373 | 42204.4 | 14 | UniProt (Q96RD7) Pfam (PF00876) | Homo sapiens (Human) | |
| 2 | AB, BA, CA, CC, DC... (G, C, L, H, D...) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 28 | Chemie (PTY) | |||
| 3 | BB, DA, EC, GB, JA... (G, C, L, H, D...) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 14 | Chemie (3PE) | |||
| 4 | AA, BC, GA, HC, JB... (B, K, C, L, H...) | DIACYL GLYCEROL | non-polymer | 625.0 | 14 | Chemie (DGA) | |||
| 5 | AC, CB, DB, EA, FA... (K, G, C, L, H...) | CHOLESTEROL | non-polymer | 386.7 | 28 | Chemie (CLR) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N: 1 - 373 (UniProt: Q96RD7)
| PDB | External Database | Details |
|---|---|---|
| Ala 255 | Asn 255 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 590861.9 | |
| Non-Polymers* | Number of molecules | 84 |
| Total formula weight | 50602.6 | |
| All* | Total formula weight | 641464.4 |
