6V14
Crystal structure of the bromodomain of human BRD9 bound to TP472
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 9 | polymer | 123 | 14249.8 | 1 | UniProt (Q9H8M2) Pfam (PF00439) | Homo sapiens (Human) | Rhabdomyosarcoma antigen MU-RMS-40.8 |
| 2 | B (A) | 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methylbenzamide | non-polymer | 333.4 | 1 | Chemie (QMG) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A: 130 - 250 (UniProt: Q9H8M2)
| PDB | External Database | Details |
|---|---|---|
| Ser 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14249.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 395.5 | |
| All* | Total formula weight | 14645.2 |
