6V14
Crystal structure of the bromodomain of human BRD9 bound to TP472
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue QMG A 301 |
| Chain | Residue |
| A | PHE160 |
| A | VAL165 |
| A | ILE169 |
| A | ASN216 |
| A | TYR222 |
| A | LYS227 |
| A | HOH416 |
| A | HOH471 |
| A | HOH480 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | ARG150 |
| A | MET213 |
| A | THR214 |
| A | ASN216 |
| A | ARG217 |
| A | PRO218 |
| A | HOH452 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding => ECO:0000269|PubMed:26365797 |
| Chain | Residue | Details |
| A | ILE169 | |
| A | TYR222 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q3UQU0 |
| Chain | Residue | Details |
| A | GLY172 |
