6TVE
Unliganded human CD73 (5'-nucleotidase) in the open state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | P | 5'-nucleotidase | polymer | 546 | 60464.3 | 1 | UniProt (P21589) Pfam (PF00149) Pfam (PF02872) In PDB | Homo sapiens (Human) | 5'-NT,Ecto-5'-nucleotidase |
2 | P | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
3 | P | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | P | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 8 | Chemie (DMS) | |||
5 | P | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
6 | water | water | 18.0 | 685 | Chemie (HOH) |
Sequence modifications
P: 27 - 549 (UniProt: P21589)
PDB | External Database | Details |
---|---|---|
Met 4 | - | initiating methionine |
Ala 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
Val 12 | - | expression tag |
Gly 13 | - | expression tag |
Thr 14 | - | expression tag |
Gly 15 | - | expression tag |
Ser 16 | - | expression tag |
Asn 17 | - | expression tag |
Asp 18 | - | expression tag |
Asp 19 | - | expression tag |
Asp 20 | - | expression tag |
Asp 21 | - | expression tag |
Lys 22 | - | expression tag |
Ser 23 | - | expression tag |
Pro 24 | - | expression tag |
Asp 25 | - | expression tag |
Pro 26 | - | expression tag |
Asp 53 | Asn 53 | conflict |
Ser 145 | Lys 145 | conflict |
Ser 147 | Lys 147 | conflict |
Asp 311 | Asn 311 | conflict |
Asp 333 | Asn 333 | conflict |
Ala 376 | Thr 376 | conflict |
Asp 403 | Asn 403 | conflict |
Ser 478 | Lys 478 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 60464.3 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1072.2 | |
All* | Total formula weight | 61536.6 |