6S4U
LXRbeta ligand binding domain in comlpex with small molecule inhibitors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C (A, B, C) | Oxysterols receptor LXR-beta | polymer | 245 | 28271.5 | 3 | UniProt (P55055) Pfam (PF00104) | Homo sapiens (Human) | Liver X receptor beta,Nuclear receptor NER,Nuclear receptor subfamily 1 group H member 2,Ubiquitously-expressed nuclear receptor |
2 | D, E, F (A, B, C) | 6-[4-[[3-oxidanyl-1,1-bis(oxidanylidene)-5-phenyl-2-propan-2-yl-3~{H}-1,2-thiazol-4-yl]amino]butyl]pyridine-2-sulfonamide | non-polymer | 480.6 | 3 | Chemie (KVK) | |||
3 | G, H, I (A, B, C) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 84814.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1441.8 | |
All* | Total formula weight | 86256.2 |