6S4U

LXRbeta ligand binding domain in comlpex with small molecule inhibitors

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X06DA
Synchrotron site	SLS
Beamline	X06DA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2009-01-15
Detector	DECTRIS PILATUS 2M
Wavelength(s)	1
Spacegroup name	P 32 2 1
Unit cell lengths	125.086, 125.086, 137.054
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	20.000 - 2.810
Rwork	0.253
R-free	0.27980
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.012
RMSD bond angle	1.593
Data reduction software	XDS
Data scaling software	XSCALE
Phasing software	MOLREP
Refinement software	REFMAC (5.8.0135 2015/10/01)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	20.000	2.900
High resolution limit [Å]	2.810	2.810
Number of reflections	30616	5170
<I/σ(I)>	16.56
Completeness [%]	99.8
Redundancy	6.6

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION		293	Unknown.