6PZV
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F (A, B, E, F) | Ubiquitin | polymer | 77 | 8710.0 | 4 | UniProt (J3QS39) Pfam (PF00240) UniProt (by SIFTS) (P0CG47) | Homo sapiens (Human) | |
| 2 | C, G (C, G) | DNA (cytosine-5)-methyltransferase 1 | polymer | 247 | 28002.5 | 2 | UniProt (Q24K09) Pfam (PF12047) | Bos taurus (Bovine) | Dnmt1 |
| 3 | D, H (D, H) | Histone H3.3 | polymer | 26 | 2810.3 | 2 | UniProt (P84243) | Homo sapiens | |
| 4 | I (C) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 5 | J, K (C, G) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | L, M, N, O, P... (A, B, C, E, F...) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A, B, E, F: 1 - 76 (UniProt: J3QS39)
C, G: 349 - 594 (UniProt: Q24K09)
D, H: 1 - 26 (UniProt: P84243)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Cys 76 | Gly 76 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 348 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Cys 18 | Lys 19 | conflict |
| Cys 23 | Lys 24 | conflict |
| Trp 26 | Arg 27 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 96465.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 319.9 | |
| All* | Total formula weight | 96785.5 |
