6PZV

Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, E, F	Ubiquitin	polymer	77	8710.0	4	UniProt (J3QS39) Pfam (PF00240) UniProt (by SIFTS) (P0CG47) In PDB	Homo sapiens (Human)
2	C, G	DNA (cytosine-5)-methyltransferase 1	polymer	247	28002.5	2	UniProt (Q24K09) Pfam (PF12047) In PDB	Bos taurus (Bovine)	Dnmt1
3	D, H	Histone H3.3	polymer	26	2810.3	2	UniProt (P84243) In PDB	Homo sapiens
4	C	CITRATE ANION	non-polymer		189.1	1	Chemie (FLC)
5	C, G	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
6		water	water		18.0	48	Chemie (HOH)

Sequence modifications

A, B, E, F: 1 - 76 (UniProt: J3QS39)

PDB	External Database	Details
Ser 0	-	expression tag
Cys 76	Gly 76	conflict

C, G: 349 - 594 (UniProt: Q24K09)

PDB	External Database	Details
Ser 348	-	expression tag

D, H: 1 - 26 (UniProt: P84243)

PDB	External Database	Details
Cys 18	Lys 19	conflict
Cys 23	Lys 24	conflict
Trp 26	Arg 27	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	96465.5
Non-Polymers*	Number of molecules	3
	Total formula weight	319.9
All*	Total formula weight	96785.5

*Water molecules are not included.