6PQ3
Crystal structure of GDP-bound KRAS with ten residues long internal tandem duplication in the switch II region
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTPase KRas | polymer | 180 | 20462.0 | 1 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E, F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | I (A) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 1 - 179 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ile 65 | - | insertion |
| Leu 66 | - | insertion |
| Asp 67 | - | insertion |
| Thr 68 | - | insertion |
| Ala 69 | - | insertion |
| Gly 70 | - | insertion |
| Gln 71 | - | insertion |
| Glu 72 | - | insertion |
| Glu 73 | - | insertion |
| Tyr 74 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20462.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 947.8 | |
| All* | Total formula weight | 21409.8 |
