6PQ3
Crystal structure of GDP-bound KRAS with ten residues long internal tandem duplication in the switch II region
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTPase KRas | polymer | 180 | 20462.0 | 1 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D, E, F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | I (A) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 1 - 179 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ile 65 | - | insertion |
| Leu 66 | - | insertion |
| Asp 67 | - | insertion |
| Thr 68 | - | insertion |
| Ala 69 | - | insertion |
| Gly 70 | - | insertion |
| Gln 71 | - | insertion |
| Glu 72 | - | insertion |
| Glu 73 | - | insertion |
| Tyr 74 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20462.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 947.8 | |
| All* | Total formula weight | 21409.8 |
