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6PJV

Structure of Human Sonic Hedgehog in complex with Zinc and Magnesium

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sonic hedgehog proteinpolymer16919122.51UniProt (Q15465)
Pfam (PF01085)
Homo sapiens (Human)SHH,HHG-1,Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains,ShhNC
2B, C, D
(A)
DIMETHYL SULFOXIDEnon-polymer78.13Chemie (DMS)
3E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4F, H
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
5G
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
6I, J
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
7K
(A)
waterwater18.0252Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19122.5
Non-Polymers*Number of molecules9
Total formula weight511.4
All*Total formula weight19633.9
*Water molecules are not included.

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PDB entries from 2026-01-21

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