6PCM
Crystal Structure of Mycobacterium smegmatis Topoisomerase I with ssDNA bound to both N- and C-terminal domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA topoisomerase 1 | polymer | 842 | 92589.5 | 2 | UniProt (A0R5D9) Pfam (PF01751) Pfam (PF01131) Pfam (PF13368) | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) | DNA topoisomerase I |
| 2 | C, D (C, D) | DNA (5'-D(P*AP*GP*TP*GP*AP*GP*CP*GP*AP*GP*CP*TP*TP*CP*CP*GP*CP*TP*TP*GP*AP*CP*TP*T)-3') | polymer | 25 | 7665.9 | 2 | Mycolicibacterium smegmatis | ||
| 3 | E, F, G, H, I... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 22 | Chemie (SO4) |
Sequence modifications
A, B: 1 - 839 (UniProt: A0R5D9)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 200510.8 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 2113.4 | |
| All* | Total formula weight | 202624.2 |
