6P3A
Crystal Structure Analysis of TAF1 Bromodomain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transcription initiation factor TFIID subunit 1 | polymer | 137 | 15882.8 | 2 | UniProt (P21675) Pfam (PF00439) | Homo sapiens (Human) | Cell cycle gene 1 protein,TBP-associated factor 250 kDa,p250,Transcription initiation factor TFIID 250 kDa subunit,TAFII250 |
| 2 | C, D (A, B) | 4-{[(3R)-1-(but-3-en-1-yl)-3-methyl-4-(oxan-4-yl)-2-oxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-6-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | non-polymer | 562.7 | 2 | Chemie (NQP) | |||
| 3 | E (A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, B: 1522 - 1656 (UniProt: P21675)
| PDB | External Database | Details |
|---|---|---|
| Ser 1520 | - | expression tag |
| Met 1521 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31765.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1125.4 | |
| All* | Total formula weight | 32891.0 |
