6P3A
Crystal Structure Analysis of TAF1 Bromodomain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0005669 | cellular_component | transcription factor TFIID complex |
| A | 0006366 | biological_process | transcription by RNA polymerase II |
| A | 0016251 | molecular_function | RNA polymerase II general transcription initiation factor activity |
| A | 0017025 | molecular_function | TBP-class protein binding |
| B | 0004402 | molecular_function | histone acetyltransferase activity |
| B | 0005669 | cellular_component | transcription factor TFIID complex |
| B | 0006366 | biological_process | transcription by RNA polymerase II |
| B | 0016251 | molecular_function | RNA polymerase II general transcription initiation factor activity |
| B | 0017025 | molecular_function | TBP-class protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue NQP A 4000 |
| Chain | Residue |
| A | PHE1530 |
| A | ASN1604 |
| A | TYR1610 |
| A | ASN1534 |
| A | TRP1547 |
| A | PRO1548 |
| A | PHE1549 |
| A | VAL1558 |
| A | TYR1561 |
| A | MET1569 |
| A | TYR1603 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide NQP B 4000 and TRP B 1547 |
| Chain | Residue |
| A | GLU1607 |
| A | GLN1609 |
| B | PHE1530 |
| B | ASN1534 |
| B | GLN1538 |
| B | ASP1545 |
| B | SER1546 |
| B | PRO1548 |
| B | PHE1549 |
| B | HIS1550 |
| B | VAL1553 |
| B | VAL1558 |
| B | TYR1561 |
| B | TYR1603 |
| B | ASN1604 |
| B | TYR1610 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. SwpFhhpvNkkfvp..DYYkvIvnpMdletIrkniskhk..Yqsresflddvnl.IlaNSvkY |
| Chain | Residue | Details |
| A | SER1546-TYR1603 |
