6NQT

GalNac-T2 soaked with UDP-sugar

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Polypeptide N-acetylgalactosaminyltransferase 2	polymer	571	64739.6	6	UniProt (Q10471) Pfam (PF00535) Pfam (PF00652) In PDB	Homo sapiens (Human)	Polypeptide GalNAc transferase 2,pp-GaNTase 2,Protein-UDP acetylgalactosaminyltransferase 2,UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2
2	A, B, C, D, E...	MANGANESE (II) ION	non-polymer		54.9	6	Chemie (MN)
3	A, B, C, D, E...	[[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R},6~{R})-3-(hex-5-ynoylamino)-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl] hydrogen phosphate	non-polymer		659.4	6	Chemie (LR7)
4		water	water		18.0	189	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 571 (UniProt: Q10471)

PDB	External Database	Details
Ala 253	Ile 253	engineered mutation
Ala 310	Leu 310	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	388437.4
Non-Polymers*	Number of molecules	12
	Total formula weight	4286.2
All*	Total formula weight	392723.6

*Water molecules are not included.