6NQT

GalNac-T2 soaked with UDP-sugar

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0002639	biological_process	positive regulation of immunoglobulin production
A	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0005795	cellular_component	Golgi stack
A	0006493	biological_process	protein O-linked glycosylation
A	0016020	cellular_component	membrane
A	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
A	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
A	0030145	molecular_function	manganese ion binding
A	0032580	cellular_component	Golgi cisterna membrane
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0051604	biological_process	protein maturation
B	0000139	cellular_component	Golgi membrane
B	0002639	biological_process	positive regulation of immunoglobulin production
B	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005794	cellular_component	Golgi apparatus
B	0005795	cellular_component	Golgi stack
B	0006493	biological_process	protein O-linked glycosylation
B	0016020	cellular_component	membrane
B	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
B	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
B	0030145	molecular_function	manganese ion binding
B	0032580	cellular_component	Golgi cisterna membrane
B	0048471	cellular_component	perinuclear region of cytoplasm
B	0051604	biological_process	protein maturation
C	0000139	cellular_component	Golgi membrane
C	0002639	biological_process	positive regulation of immunoglobulin production
C	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005794	cellular_component	Golgi apparatus
C	0005795	cellular_component	Golgi stack
C	0006493	biological_process	protein O-linked glycosylation
C	0016020	cellular_component	membrane
C	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
C	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
C	0030145	molecular_function	manganese ion binding
C	0032580	cellular_component	Golgi cisterna membrane
C	0048471	cellular_component	perinuclear region of cytoplasm
C	0051604	biological_process	protein maturation
D	0000139	cellular_component	Golgi membrane
D	0002639	biological_process	positive regulation of immunoglobulin production
D	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0005794	cellular_component	Golgi apparatus
D	0005795	cellular_component	Golgi stack
D	0006493	biological_process	protein O-linked glycosylation
D	0016020	cellular_component	membrane
D	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
D	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
D	0030145	molecular_function	manganese ion binding
D	0032580	cellular_component	Golgi cisterna membrane
D	0048471	cellular_component	perinuclear region of cytoplasm
D	0051604	biological_process	protein maturation
E	0000139	cellular_component	Golgi membrane
E	0002639	biological_process	positive regulation of immunoglobulin production
E	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0005794	cellular_component	Golgi apparatus
E	0005795	cellular_component	Golgi stack
E	0006493	biological_process	protein O-linked glycosylation
E	0016020	cellular_component	membrane
E	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
E	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
E	0030145	molecular_function	manganese ion binding
E	0032580	cellular_component	Golgi cisterna membrane
E	0048471	cellular_component	perinuclear region of cytoplasm
E	0051604	biological_process	protein maturation
F	0000139	cellular_component	Golgi membrane
F	0002639	biological_process	positive regulation of immunoglobulin production
F	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0005794	cellular_component	Golgi apparatus
F	0005795	cellular_component	Golgi stack
F	0006493	biological_process	protein O-linked glycosylation
F	0016020	cellular_component	membrane
F	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
F	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
F	0030145	molecular_function	manganese ion binding
F	0032580	cellular_component	Golgi cisterna membrane
F	0048471	cellular_component	perinuclear region of cytoplasm
F	0051604	biological_process	protein maturation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MN A 701

Chain	Residue
A	ASP224
A	HIS226
A	HIS359
A	LR7702

---

site_id	AC2
Number of Residues	25
Details	binding site for residue LR7 A 702

Chain	Residue
A	GLY203
A	LEU204
A	ARG208
A	ASP224
A	SER225
A	HIS226
A	ALA253
A	ALA307
A	GLY308
A	GLY309
A	ALA310
A	VAL330
A	TRP331
A	GLY332
A	GLU334
A	VAL357
A	HIS359
A	ARG362
A	TYR367
A	MN701
A	THR143
A	PHE144
A	HIS145
A	ASP176
A	ARG201

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MN B 701

Chain	Residue
B	ASP224
B	HIS226
B	HIS359
B	LR7702

---

site_id	AC4
Number of Residues	26
Details	binding site for residue LR7 B 702

Chain	Residue
B	THR143
B	PHE144
B	HIS145
B	ASP176
B	ARG201
B	GLY203
B	LEU204
B	ARG208
B	ASP224
B	SER225
B	HIS226
B	ALA253
B	ALA307
B	GLY308
B	GLY309
B	ALA310
B	VAL330
B	TRP331
B	GLU334
B	ASN335
B	VAL357
B	HIS359
B	ARG362
B	TYR367
B	MN701
B	HOH805

---

site_id	AC5
Number of Residues	4
Details	binding site for residue MN C 701

Chain	Residue
C	ASP224
C	HIS226
C	HIS359
C	LR7702

---

site_id	AC6
Number of Residues	23
Details	binding site for residue LR7 C 702

Chain	Residue
C	THR143
C	PHE144
C	ASP176
C	ARG201
C	GLY203
C	LEU204
C	ARG208
C	ASP224
C	SER225
C	HIS226
C	ALA307
C	GLY308
C	GLY309
C	ALA310
C	VAL330
C	TRP331
C	GLY332
C	GLU334
C	VAL357
C	HIS359
C	ARG362
C	TYR367
C	MN701

---

site_id	AC7
Number of Residues	4
Details	binding site for residue MN D 701

Chain	Residue
D	ASP224
D	HIS226
D	HIS359
D	LR7702

---

site_id	AC8
Number of Residues	21
Details	binding site for residue LR7 D 702

Chain	Residue
D	HIS226
D	ALA253
D	ALA307
D	GLY308
D	GLY309
D	TRP331
D	GLU334
D	ASN335
D	HIS359
D	PHE361
D	TYR367
D	MN701
D	THR143
D	PHE144
D	ASP176
D	ARG201
D	GLY203
D	LEU204
D	ARG208
D	ASP224
D	SER225

---

site_id	AC9
Number of Residues	4
Details	binding site for residue MN E 701

Chain	Residue
E	ASP224
E	HIS226
E	HIS359
E	LR7702

---

site_id	AD1
Number of Residues	23
Details	binding site for residue LR7 E 702

Chain	Residue
E	THR143
E	PHE144
E	HIS145
E	ASP176
E	ARG201
E	LEU204
E	ARG208
E	ASP224
E	SER225
E	HIS226
E	ALA253
E	ALA307
E	GLY308
E	GLY309
E	ALA310
E	VAL330
E	TRP331
E	GLU334
E	ASN335
E	VAL357
E	HIS359
E	ARG362
E	MN701

---

site_id	AD2
Number of Residues	4
Details	binding site for residue MN F 701

Chain	Residue
F	ASP224
F	HIS226
F	HIS359
F	LR7702

---

site_id	AD3
Number of Residues	26
Details	binding site for residue LR7 F 702

Chain	Residue
F	THR143
F	PHE144
F	HIS145
F	ASP176
F	ARG201
F	LEU204
F	ARG208
F	ASP224
F	SER225
F	HIS226
F	CYS227
F	ALA307
F	GLY308
F	GLY309
F	ALA310
F	VAL330
F	TRP331
F	GLY332
F	GLU334
F	ASN335
F	VAL357
F	HIS359
F	ARG362
F	HIS365
F	TYR367
F	MN701

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	615
Details	Domain: {"description":"Ricin B-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00174","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	630
Details	Region: {"description":"Catalytic subdomain A"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	372
Details	Region: {"description":"Catalytic subdomain B"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	42
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16434399","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24954443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25939779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D11","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FV9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16434399","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24954443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25939779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D0Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D11","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FV9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16434399","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24954443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25939779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D0Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D11","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5NDF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6EGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	Site: {"description":"Not glycosylated"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---