6MS7
Peroxisome proliferator-activated receptor gamma ligand binding domain in complex with a novel selective PPAR-gamma modulator VSP-77
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peroxisome proliferator-activated receptor gamma | polymer | 274 | 31238.3 | 1 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | B | PGC1 LXXLL motif | polymer | 11 | 1194.5 | 1 | UniProt (by SIFTS) (Q9UBK2) In PDB | synthetic construct | |
| 3 | A | {[(1S)-1-(4-chlorophenyl)octyl]oxy}acetic acid | non-polymer | 298.8 | 2 | Chemie (V77) | |||
| 4 | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 206 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 204 | - | expression tag |
| Ser 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32432.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 597.6 | |
| All* | Total formula weight | 33030.4 |
