6MII

Crystal structure of minichromosome maintenance protein MCM/DNA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Minichromosome maintenance protein MCM	polymer	610	68642.0	6	UniProt (Q9UXG1) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855)	Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
2	G (X)	DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')	polymer	12	3605.4	1		synthetic construct
3	H, K, N (A, B, C)	[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium	non-polymer		492.2	3	Chemie (08T)
4	I, L, O, R, U... (A, B, C, D, E...)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
5	J, M, P, S, V... (A, B, C, D, E...)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
6	Q, T, W (D, E, F)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	3	Chemie (ADP)
7	AA, BA, CA, DA, EA... (B, C, D, E, F...)	water	water		18.0	18	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 2 - 265 (UniProt: Q9UXG1)

PDB	External Database	Details
Ser 0	-	expression tag
Leu 1	-	expression tag

A, B, C, D, E, F: 275 - 612 (UniProt: Q9UXG1)

PDB	External Database	Details
Gly 269	-	linker
Gly 270	-	linker
Ser 271	-	linker
Gly 272	-	linker
Gly 273	-	linker
Ser 274	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	415457.1
Non-Polymers*	Number of molecules	18
	Total formula weight	3296.5
All*	Total formula weight	418753.6

*Water molecules are not included.