6MCQ
L. pneumophila effector kinase LegK7 in complex with human MOB1A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | LegK7 | polymer | 523 | 60684.2 | 2 | UniProt (Q5ZU83) | Legionella pneumophila subsp. pneumophila | |
| 2 | B, D (B, D) | MOB kinase activator 1A | polymer | 187 | 21669.7 | 2 | UniProt (Q9H8S9) Pfam (PF03637) | Homo sapiens (Human) | Mob1 alpha, Mob1A, Mob1 homolog 1B, Mps one binder kinase activator-like 1B |
| 3 | BA, CA, DA, E, F... (D, A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 16 | Chemie (PEG) | |||
| 4 | I, M, T (A, B) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 3 | Chemie (P6G) | |||
| 5 | AA, L, P, U, V (D, A, B, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 5 | Chemie (PG4) | |||
| 6 | R, Z (B, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 7 | EA, FA, GA, HA (A, B, C, D) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A, C: 11 - 530 (UniProt: Q5ZU83)
B, D: 33 - 216 (UniProt: Q9H8S9)
| PDB | External Database | Details |
|---|---|---|
| Ser 8 | - | expression tag |
| Asn 9 | - | expression tag |
| Ala 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 30 | - | expression tag |
| Asn 31 | - | expression tag |
| Ala 32 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 164707.8 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 3646.9 | |
| All* | Total formula weight | 168354.7 |
