6MCQ

L. pneumophila effector kinase LegK7 in complex with human MOB1A

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue PEG A 601

Chain	Residue
A	LYS69

---

site_id	AC2
Number of Residues	2
Details	binding site for residue PEG A 602

Chain	Residue
A	LYS37
A	GLU119

---

site_id	AC3
Number of Residues	4
Details	binding site for residue PEG A 603

Chain	Residue
A	LYS28
A	LYS69
A	PHE70
A	PEG604

---

site_id	AC4
Number of Residues	3
Details	binding site for residue PEG A 604

Chain	Residue
A	PEG603
A	GLU25
A	LYS28

---

site_id	AC5
Number of Residues	5
Details	binding site for residue P6G A 605

Chain	Residue
A	LYS163
A	ALA166
A	PHE197
C	GLN271
C	ASP274

---

site_id	AC6
Number of Residues	2
Details	binding site for residue PEG A 606

Chain	Residue
A	ARG367
A	ASN368

---

site_id	AC7
Number of Residues	5
Details	binding site for residue PEG A 607

Chain	Residue
A	LYS309
A	ASN311
A	SER342
A	PRO343
A	LEU344

---

site_id	AC8
Number of Residues	5
Details	binding site for residue PG4 A 608

Chain	Residue
A	GLN262
A	GLN271
A	ASN317
A	ASN318
B	GLY73

---

site_id	AC9
Number of Residues	10
Details	binding site for residue P6G A 609

Chain	Residue
A	TYR107
A	ILE149
A	PHE231
A	GLU233
A	HOH707
A	HOH712
A	HOH748
B	GLN172
B	LEU173
B	GLN174

---

site_id	AD1
Number of Residues	3
Details	binding site for residue PEG A 610

Chain	Residue
A	THR341
A	PRO343
A	PRO362

---

site_id	AD2
Number of Residues	2
Details	binding site for residue PEG A 611

Chain	Residue
A	TYR365
A	LEU370

---

site_id	AD3
Number of Residues	4
Details	binding site for residue PG4 A 612

Chain	Residue
A	LYS124
A	CYS125
A	THR127
A	ARG128

---

site_id	AD4
Number of Residues	1
Details	binding site for residue PEG A 613

Chain	Residue
A	GLN111

---

site_id	AD5
Number of Residues	4
Details	binding site for residue ZN B 301

Chain	Residue
B	CYS79
B	CYS84
B	HIS161
B	HIS166

---

site_id	AD6
Number of Residues	2
Details	binding site for residue PEG B 302

Chain	Residue
B	HIS164
B	HOH402

---

site_id	AD7
Number of Residues	5
Details	binding site for residue P6G B 303

Chain	Residue
B	MET145
B	LYS149
B	PHE193
B	ASN194
B	ASP197

---

site_id	AD8
Number of Residues	1
Details	binding site for residue PG4 B 304

Chain	Residue
A	THR13

---

site_id	AD9
Number of Residues	5
Details	binding site for residue PG4 C 601

Chain	Residue
C	GLN115
C	LYS124
C	THR127
C	ARG128
C	LYS444

---

site_id	AE1
Number of Residues	3
Details	binding site for residue PEG C 602

Chain	Residue
C	LYS28
C	LYS69
C	PHE70

---

site_id	AE2
Number of Residues	3
Details	binding site for residue PEG C 603

Chain	Residue
C	LYS309
C	ASN311
C	SER342

---

site_id	AE3
Number of Residues	2
Details	binding site for residue PEG C 604

Chain	Residue
C	GLN111
C	GLU112

---

site_id	AE4
Number of Residues	4
Details	binding site for residue ZN D 301

Chain	Residue
D	CYS79
D	CYS84
D	HIS161
D	HIS166

---

site_id	AE5
Number of Residues	2
Details	binding site for residue PG4 D 302

Chain	Residue
D	MET145
D	LYS149

---

site_id	AE6
Number of Residues	1
Details	binding site for residue PEG D 303

Chain	Residue
D	TYR163

---

site_id	AE7
Number of Residues	4
Details	binding site for residue PEG D 304

Chain	Residue
C	PHE79
C	TYR107
C	GLU233
D	GLN174

---

site_id	AE8
Number of Residues	3
Details	binding site for residue PEG D 305

Chain	Residue
C	ARG152
D	PHE78
D	LEU173

---

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. DrhelgkeqeLhsYGVSKYFIeDYSvFMM

Chain	Residue	Details
A	ASP212-MET240

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12962634","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18328708","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine; by STK3/MST2","evidences":[{"source":"PubMed","id":"18362890","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18362890","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---