6MAJ
HBO1 is required for the maintenance of leukaemia stem cells
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone acetyltransferase KAT7 | polymer | 279 | 32872.3 | 1 | UniProt (O95251) Pfam (PF17772) Pfam (PF01853) | Homo sapiens (Human) | Histone acetyltransferase binding to ORC1,Lysine acetyltransferase 7,MOZ,YBF2/SAS3,SAS2 and TIP60 protein 2,MYST-2 |
| 2 | B (B) | BRD1 protein | polymer | 52 | 5843.4 | 1 | UniProt (Q86X06) UniProt (by SIFTS) (O95696) | Homo sapiens (Human) | |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F (A) | 4-fluoro-N'-[(3-hydroxyphenyl)sulfonyl]-5-methyl[1,1'-biphenyl]-3-carbohydrazide | non-polymer | 400.4 | 1 | Chemie (JAV) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A: 336 - 609 (UniProt: O95251)
B: 31 - 80 (UniProt: Q86X06)
| PDB | External Database | Details |
|---|---|---|
| Met 333 | - | initiating methionine |
| Gly 334 | - | expression tag |
| Ser 335 | - | expression tag |
| Ala 610 | - | expression tag |
| Ser 611 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 29 | - | expression tag |
| Ser 30 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38715.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 650.0 | |
| All* | Total formula weight | 39365.8 |
