6M11
Crystal structure of Rnase L in complex with Sunitinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (a, b) | Ribonuclease L | polymer | 717 | 81327.8 | 2 | UniProt (A5H025) | Sus scrofa (Pig) | |
| 2 | C, E (a, b) | 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE | non-polymer | 1005.6 | 2 | Chemie (25A) | |||
| 3 | D, F (a, b) | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | non-polymer | 398.5 | 2 | Chemie (B49) | |||
| 4 | G (b) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | H, I (a, b) | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
a, b: 21 - 732 (UniProt: A5H025)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Met 18 | - | expression tag |
| Asp 19 | - | expression tag |
| Pro 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 162655.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2903.2 | |
| All* | Total formula weight | 165558.9 |
