Functional Information from GO Data
| Chain | GOid | namespace | contents |
| a | 0004540 | molecular_function | RNA nuclease activity |
| a | 0004672 | molecular_function | protein kinase activity |
| a | 0005524 | molecular_function | ATP binding |
| a | 0006397 | biological_process | mRNA processing |
| a | 0006468 | biological_process | protein phosphorylation |
| a | 0046872 | molecular_function | metal ion binding |
| b | 0004540 | molecular_function | RNA nuclease activity |
| b | 0004672 | molecular_function | protein kinase activity |
| b | 0005524 | molecular_function | ATP binding |
| b | 0006397 | biological_process | mRNA processing |
| b | 0006468 | biological_process | protein phosphorylation |
| b | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue 25A a 1000 |
| Chain | Residue |
| a | TRP56 |
| a | GLU129 |
| a | VAL132 |
| a | TYR133 |
| a | ARG153 |
| a | HOH1111 |
| a | HOH1124 |
| a | HOH1141 |
| b | ARG307 |
| b | TYR310 |
| b | ARG353 |
| a | TRP58 |
| b | HOH905 |
| a | SER63 |
| a | GLN66 |
| a | LYS87 |
| a | ASN89 |
| a | ASP120 |
| a | ASN122 |
| a | PHE124 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue B49 a 1001 |
| Chain | Residue |
| a | ILE369 |
| a | ALA370 |
| a | ILE377 |
| a | ALA388 |
| a | ALA433 |
| a | LEU434 |
| a | CYS435 |
| a | THR438 |
| a | GLU441 |
| a | GLN486 |
| a | LEU489 |
| a | HOH1118 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | binding site for residue 25A b 801 |
| Chain | Residue |
| a | ARG307 |
| a | TYR310 |
| a | ARG353 |
| a | PHE362 |
| a | HOH1126 |
| b | GLN32 |
| b | TRP56 |
| b | TRP58 |
| b | LYS87 |
| b | ASN89 |
| b | ASN122 |
| b | PHE124 |
| b | GLU129 |
| b | VAL132 |
| b | TYR133 |
| b | ARG153 |
| b | GLY165 |
| b | HOH909 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue B49 b 802 |
| Chain | Residue |
| b | ARG340 |
| b | ILE369 |
| b | ALA370 |
| b | ALA388 |
| b | ALA433 |
| b | LEU434 |
| b | CYS435 |
| b | GLU441 |
| b | LEU489 |
| b | ASP500 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 b 803 |
| Chain | Residue |
| a | ARG675 |
| a | HIS680 |
| b | ARG675 |
| b | HIS680 |
Functional Information from PROSITE/UniProt
| site_id | PS00066 |
| Number of Residues | 15 |
| Details | HMG_COA_REDUCTASE_1 Hydroxymethylglutaryl-coenzyme A reductases signature 1. KaEVdARDnMGrNaL |
| Chain | Residue | Details |
| a | LYS190-LEU204 | |
