6KQQ
NSD1 SET domain in complex with BT3 and SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific | polymer | 223 | 25364.0 | 2 | UniProt (Q96L73) Pfam (PF17907) Pfam (PF00856) | Homo sapiens (Human) | Androgen receptor coactivator 267 kDa protein,Androgen receptor-associated protein of 267 kDa,H3-K36-HMTase,H4-K20-HMTase,Lysine N-methyltransferase 3B,Nuclear receptor-binding SET domain-containing protein 1,NR-binding SET domain-containing protein |
| 2 | C, K (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
| 3 | D, L (A, B) | 2-azanyl-6-sulfanyl-1,3-benzothiazol-4-ol | non-polymer | 198.3 | 2 | Chemie (DQL) | |||
| 4 | E (A) | 2-azanyl-6-[(2-azanyl-4-oxidanyl-1,3-benzothiazol-6-yl)disulfanyl]-1,3-benzothiazol-4-ol | non-polymer | 394.5 | 1 | Chemie (DW9) | |||
| 5 | F, G, H, N, O... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 6 | I, J (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 7 | M (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | Q, R (A, B) | water | water | 18.0 | 513 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50727.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2152.6 | |
| All* | Total formula weight | 52880.6 |
