6KQQ
NSD1 SET domain in complex with BT3 and SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific | polymer | 223 | 25364.0 | 2 | UniProt (Q96L73) Pfam (PF17907) Pfam (PF00856) | Homo sapiens (Human) | Androgen receptor coactivator 267 kDa protein,Androgen receptor-associated protein of 267 kDa,H3-K36-HMTase,H4-K20-HMTase,Lysine N-methyltransferase 3B,Nuclear receptor-binding SET domain-containing protein 1,NR-binding SET domain-containing protein |
| 2 | C, K (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (9865603) PubChem (12312798) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (145712080) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 3 | D, L (A, B) | 2-azanyl-6-sulfanyl-1,3-benzothiazol-4-ol | non-polymer | 198.3 | 2 | Chemie (DQL) PubChem (154573901) | |||
| 4 | E (A) | 2-azanyl-6-[(2-azanyl-4-oxidanyl-1,3-benzothiazol-6-yl)disulfanyl]-1,3-benzothiazol-4-ol | non-polymer | 394.5 | 1 | Chemie (DW9) PubChem (138714094) | |||
| 5 | F, G, H, N, O... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 6 | I, J (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 7 | M (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 8 | Q, R (A, B) | water | water | 18.0 | 513 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50727.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2152.6 | |
| All* | Total formula weight | 52880.6 |
