Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0042054 | molecular_function | histone methyltransferase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0042054 | molecular_function | histone methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue SAM A 2101 |
| Chain | Residue |
| A | ARG1952 |
| A | HIS2021 |
| A | TYR2058 |
| A | VAL2069 |
| A | CYS2070 |
| A | LYS2071 |
| A | LEU2081 |
| A | DQL2102 |
| A | HOH2219 |
| A | HOH2232 |
| A | HOH2266 |
| A | TRP1954 |
| A | HOH2378 |
| A | THR1994 |
| A | ASN1995 |
| A | PHE1996 |
| A | TYR1997 |
| A | ARG2017 |
| A | MET2019 |
| A | ASN2020 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue DQL A 2102 |
| Chain | Residue |
| A | THR1994 |
| A | PHE1996 |
| A | TYR2058 |
| A | CYS2062 |
| A | LEU2063 |
| A | ASN2065 |
| A | GLY2066 |
| A | THR2068 |
| A | GLY2082 |
| A | SAM2101 |
| A | HOH2230 |
| A | HOH2377 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | binding site for residue DW9 A 2103 |
| Chain | Residue |
| A | ASP1864 |
| A | LYS1865 |
| A | LYS1866 |
| A | PRO1867 |
| A | LYS1871 |
| A | ILE1946 |
| A | GLY2010 |
| A | PRO2011 |
| A | LYS2012 |
| A | ASN2014 |
| A | TYR2015 |
| A | ARG2017 |
| A | PHE2018 |
| A | HOH2206 |
| A | HOH2231 |
| A | HOH2287 |
| A | HOH2316 |
| A | HOH2331 |
| A | HOH2387 |
| A | HOH2390 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2104 |
| Chain | Residue |
| A | CYS2023 |
| A | CYS2070 |
| A | CYS2072 |
| A | CYS2077 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2105 |
| Chain | Residue |
| A | CYS1905 |
| A | CYS1920 |
| A | CYS1925 |
| A | CYS1931 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2106 |
| Chain | Residue |
| A | CYS1895 |
| A | CYS1897 |
| A | CYS1905 |
| A | CYS1911 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 2107 |
| Chain | Residue |
| A | GLU1910 |
| A | HOH2282 |
| B | GLU1978 |
| B | LYS2003 |
| B | HOH2285 |
| B | HOH2304 |
| B | HOH2305 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 2108 |
| Chain | Residue |
| A | GLU1978 |
| A | LYS2003 |
| A | HOH2298 |
| A | HOH2401 |
| B | HOH2216 |
| B | HOH2290 |
| site_id | AC9 |
| Number of Residues | 19 |
| Details | binding site for residue SAM B 2101 |
| Chain | Residue |
| B | ARG1952 |
| B | TRP1954 |
| B | THR1994 |
| B | ASN1995 |
| B | PHE1996 |
| B | TYR1997 |
| B | ARG2017 |
| B | ASN2020 |
| B | HIS2021 |
| B | TYR2058 |
| B | VAL2069 |
| B | CYS2070 |
| B | LYS2071 |
| B | LEU2081 |
| B | DQL2102 |
| B | HOH2211 |
| B | HOH2260 |
| B | HOH2271 |
| B | HOH2292 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for residue GOL B 2103 |
| Chain | Residue |
| B | ILE1892 |
| B | PRO1893 |
| B | ARG1894 |
| B | HOH2210 |
| B | HOH2255 |
| B | HOH2273 |
| B | HOH2311 |
| A | PRO1869 |
| A | LYS2067 |
| B | SER1890 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 2104 |
| Chain | Residue |
| B | CYS1905 |
| B | CYS1920 |
| B | CYS1925 |
| B | CYS1931 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 2105 |
| Chain | Residue |
| B | CYS1895 |
| B | CYS1897 |
| B | CYS1905 |
| B | CYS1911 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 2106 |
| Chain | Residue |
| B | CYS2023 |
| B | CYS2070 |
| B | CYS2072 |
| B | CYS2077 |
| site_id | AD5 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide DQL B 2102 and CYS B 2062 |
| Chain | Residue |
| B | THR1994 |
| B | PHE1996 |
| B | MET1998 |
| B | TYR2058 |
| B | GLU2061 |
| B | LEU2063 |
| B | GLY2064 |
| B | GLY2066 |
| B | THR2068 |
| B | GLY2082 |
| B | ARG2084 |
| B | SAM2101 |
| B | HOH2221 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ARG1952 | |
| A | THR1994 | |
| A | ASN2020 | |
| B | ARG1952 | |
| B | THR1994 | |
| B | ASN2020 | |
| Chain | Residue | Details |
| A | ASN2065 | |
| A | LYS2071 | |
| B | ASN2065 | |
| B | LYS2071 | |
