Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005634 | cellular_component | nucleus |
A | 0042054 | molecular_function | histone methyltransferase activity |
B | 0005634 | cellular_component | nucleus |
B | 0042054 | molecular_function | histone methyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 20 |
Details | binding site for residue SAM A 2101 |
Chain | Residue |
A | ARG1952 |
A | HIS2021 |
A | TYR2058 |
A | VAL2069 |
A | CYS2070 |
A | LYS2071 |
A | LEU2081 |
A | DQL2102 |
A | HOH2219 |
A | HOH2232 |
A | HOH2266 |
A | TRP1954 |
A | HOH2378 |
A | THR1994 |
A | ASN1995 |
A | PHE1996 |
A | TYR1997 |
A | ARG2017 |
A | MET2019 |
A | ASN2020 |
site_id | AC2 |
Number of Residues | 12 |
Details | binding site for residue DQL A 2102 |
Chain | Residue |
A | THR1994 |
A | PHE1996 |
A | TYR2058 |
A | CYS2062 |
A | LEU2063 |
A | ASN2065 |
A | GLY2066 |
A | THR2068 |
A | GLY2082 |
A | SAM2101 |
A | HOH2230 |
A | HOH2377 |
site_id | AC3 |
Number of Residues | 20 |
Details | binding site for residue DW9 A 2103 |
Chain | Residue |
A | ASP1864 |
A | LYS1865 |
A | LYS1866 |
A | PRO1867 |
A | LYS1871 |
A | ILE1946 |
A | GLY2010 |
A | PRO2011 |
A | LYS2012 |
A | ASN2014 |
A | TYR2015 |
A | ARG2017 |
A | PHE2018 |
A | HOH2206 |
A | HOH2231 |
A | HOH2287 |
A | HOH2316 |
A | HOH2331 |
A | HOH2387 |
A | HOH2390 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue ZN A 2104 |
Chain | Residue |
A | CYS2023 |
A | CYS2070 |
A | CYS2072 |
A | CYS2077 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue ZN A 2105 |
Chain | Residue |
A | CYS1905 |
A | CYS1920 |
A | CYS1925 |
A | CYS1931 |
site_id | AC6 |
Number of Residues | 4 |
Details | binding site for residue ZN A 2106 |
Chain | Residue |
A | CYS1895 |
A | CYS1897 |
A | CYS1905 |
A | CYS1911 |
site_id | AC7 |
Number of Residues | 7 |
Details | binding site for residue CA A 2107 |
Chain | Residue |
A | GLU1910 |
A | HOH2282 |
B | GLU1978 |
B | LYS2003 |
B | HOH2285 |
B | HOH2304 |
B | HOH2305 |
site_id | AC8 |
Number of Residues | 6 |
Details | binding site for residue CA A 2108 |
Chain | Residue |
A | GLU1978 |
A | LYS2003 |
A | HOH2298 |
A | HOH2401 |
B | HOH2216 |
B | HOH2290 |
site_id | AC9 |
Number of Residues | 19 |
Details | binding site for residue SAM B 2101 |
Chain | Residue |
B | ARG1952 |
B | TRP1954 |
B | THR1994 |
B | ASN1995 |
B | PHE1996 |
B | TYR1997 |
B | ARG2017 |
B | ASN2020 |
B | HIS2021 |
B | TYR2058 |
B | VAL2069 |
B | CYS2070 |
B | LYS2071 |
B | LEU2081 |
B | DQL2102 |
B | HOH2211 |
B | HOH2260 |
B | HOH2271 |
B | HOH2292 |
site_id | AD1 |
Number of Residues | 10 |
Details | binding site for residue GOL B 2103 |
Chain | Residue |
B | ILE1892 |
B | PRO1893 |
B | ARG1894 |
B | HOH2210 |
B | HOH2255 |
B | HOH2273 |
B | HOH2311 |
A | PRO1869 |
A | LYS2067 |
B | SER1890 |
site_id | AD2 |
Number of Residues | 4 |
Details | binding site for residue ZN B 2104 |
Chain | Residue |
B | CYS1905 |
B | CYS1920 |
B | CYS1925 |
B | CYS1931 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue ZN B 2105 |
Chain | Residue |
B | CYS1895 |
B | CYS1897 |
B | CYS1905 |
B | CYS1911 |
site_id | AD4 |
Number of Residues | 4 |
Details | binding site for residue ZN B 2106 |
Chain | Residue |
B | CYS2023 |
B | CYS2070 |
B | CYS2072 |
B | CYS2077 |
site_id | AD5 |
Number of Residues | 13 |
Details | binding site for Di-peptide DQL B 2102 and CYS B 2062 |
Chain | Residue |
B | THR1994 |
B | PHE1996 |
B | MET1998 |
B | TYR2058 |
B | GLU2061 |
B | LEU2063 |
B | GLY2064 |
B | GLY2066 |
B | THR2068 |
B | GLY2082 |
B | ARG2084 |
B | SAM2101 |
B | HOH2221 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | BINDING: |
Chain | Residue | Details |
A | ARG1952 | |
A | THR1994 | |
A | ASN2020 | |
B | ARG1952 | |
B | THR1994 | |
B | ASN2020 | |
Chain | Residue | Details |
A | ASN2065 | |
A | LYS2071 | |
B | ASN2065 | |
B | LYS2071 | |