6KI6
Crystal structure of BCL11A in complex with gamma-globin -115 HPFH region
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | B-cell lymphoma/leukemia 11A | polymer | 109 | 12644.5 | 2 | UniProt (Q9H165) Pfam (PF00096) | Homo sapiens (Human) | |
| 2 | C, F (C, F) | DNA (5'-D(*AP*TP*AP*TP*TP*GP*GP*TP*CP*AP*AP*GP*G)-3') | polymer | 13 | 4030.6 | 2 | Homo sapiens | ||
| 3 | D, E (D, E) | DNA (5'-D(*TP*CP*CP*TP*TP*GP*AP*CP*CP*AP*AP*TP*A)-3') | polymer | 13 | 3910.6 | 2 | Homo sapiens | ||
| 4 | G, H, I, J, K (A, B) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 5 | L, M, N, O, P... (A, B, C, D, E...) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A, B: 731 - 835 (UniProt: Q9H165)
| PDB | External Database | Details |
|---|---|---|
| Gly 727 | - | expression tag |
| Ser 728 | - | expression tag |
| His 729 | - | expression tag |
| Met 730 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 41171.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 327.0 | |
| All* | Total formula weight | 41498.6 |
