6KI6
Crystal structure of BCL11A in complex with gamma-globin -115 HPFH region
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | B-cell lymphoma/leukemia 11A | polymer | 109 | 12644.5 | 2 | UniProt (Q9H165) Pfam (PF00096) In PDB | Homo sapiens (Human) | |
2 | C, F | DNA (5'-D(*AP*TP*AP*TP*TP*GP*GP*TP*CP*AP*AP*GP*G)-3') | polymer | 13 | 4030.6 | 2 | Homo sapiens | ||
3 | D, E | DNA (5'-D(*TP*CP*CP*TP*TP*GP*AP*CP*CP*AP*AP*TP*A)-3') | polymer | 13 | 3910.6 | 2 | Homo sapiens | ||
4 | A, B | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
5 | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A, B: 731 - 835 (UniProt: Q9H165)
PDB | External Database | Details |
---|---|---|
Gly 727 | - | expression tag |
Ser 728 | - | expression tag |
His 729 | - | expression tag |
Met 730 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 41171.5 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 327.0 | |
All* | Total formula weight | 41498.6 |