6HYC

The structure of full-length human phenylalanine hydroxylase in complex with the cofactor and negative regulator tetrahydrobiopterin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (D, A, C, B)	Phenylalanine-4-hydroxylase	polymer	452	51928.9	4	UniProt (P00439) Pfam (PF01842) Pfam (PF00351)	Homo sapiens (Human)	PAH,Phe-4-monooxygenase
2	E, F, G (D, C, B)	5,6,7,8-TETRAHYDROBIOPTERIN	non-polymer		241.2	3	Chemie (H4B)
3	H, I, J (A, C, B)	water	water		18.0	5	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	207715.6
Non-Polymers*	Number of molecules	3
	Total formula weight	723.7
All*	Total formula weight	208439.4

*Water molecules are not included.