6ERF
Complex of APLF factor and Ku heterodimer bound to DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G | X-ray repair cross-complementing protein 6 | polymer | 544 | 62629.6 | 4 | UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) In PDB | Homo sapiens (Human) | 5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6 |
| 2 | B, D, F, H | X-ray repair cross-complementing protein 5 | polymer | 572 | 65356.8 | 4 | UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) In PDB | Homo sapiens (Human) | 86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 3 | I, K, M, O | DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3') | polymer | 21 | 6506.2 | 4 | synthetic construct | ||
| 4 | J, L, N, P | DNA (34-MER) | polymer | 34 | 10325.7 | 4 | synthetic construct | ||
| 5 | Q, R, S, T | Aprataxin and PNK-like factor | polymer | 18 | 2225.7 | 4 | UniProt (Q8IW19) In PDB | Homo sapiens | Apurinic-apyrimidinic endonuclease APLF,PNK and APTX-like FHA domain-containing protein,XRCC1-interacting protein 1 |
| 6 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
B, D, F, H: 2 - 555 (UniProt: P13010)
| PDB | External Database | Details |
|---|---|---|
| Met -16 | - | initiating methionine |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| Glu -5 | - | expression tag |
| Asn -4 | - | expression tag |
| Leu -3 | - | expression tag |
| Tyr -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Gln 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 588176.3 | |
| All* | Total formula weight | 588176.3 |
