6DNA
Crystal structure of T110A mutant human Glutamate oxaloacetate transaminase 1 (GOT1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Aspartate aminotransferase, cytoplasmic | polymer | 408 | 45785.7 | 6 | UniProt (P17174) Pfam (PF00155) | Homo sapiens (Human) | cAspAT,Cysteine aminotransferase,cytoplasmic,Cysteine transaminase,cCAT,Glutamate oxaloacetate transaminase 1,Transaminase A |
| 2 | G, I, L (A, B, D) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) | |||
| 3 | H, J, K, M, N... (A, B, C, D, E...) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 6 | Chemie (PLP) | |||
| 4 | P, Q, R, S (B, C, E, F) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 6 - 410 (UniProt: P17174)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Thr 110 | engineered mutation |
| Lys 411 | - | expression tag |
| Ile 412 | - | expression tag |
| Gln 413 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 274714.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2065.5 | |
| All* | Total formula weight | 276779.7 |
