6CBX
Crystal structure of human SET and MYND Domain Containing protein 2 with MTF1497
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | N-lysine methyltransferase SMYD2 | polymer | 434 | 49889.2 | 2 | UniProt (Q9NRG4) Pfam (PF00856) Pfam (PF01753) | Homo sapiens (Human) | HSKM-B,Histone methyltransferase SMYD2,Lysine N-methyltransferase 3C,SET and MYND domain-containing protein 2 |
| 2 | C, D, E, O, P... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | F, R (A, B) | [3-(4-amino-6-methyl-1H-imidazo[4,5-c]pyridin-1-yl)azetidin-1-yl][1-({1-[(1R)-cyclohept-2-en-1-yl]piperidin-4-yl}methyl )-1H-pyrrol-3-yl]methanone | non-polymer | 487.6 | 2 | Chemie (EW1) | |||
| 4 | G, S (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | H, I, T, U (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 6 | J, K, L, M, N... (A, B) | UNKNOWN ATOM OR ION | non-polymer | 10 | Chemie (UNX) | ||||
| 7 | AA, BA (A, B) | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 433 (UniProt: Q9NRG4)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Glu 165 | Gly 165 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 99778.4 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 1686.9 | |
| All* | Total formula weight | 101465.3 |
