6CBX

Crystal structure of human SET and MYND Domain Containing protein 2 with MTF1497

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 19-ID
Synchrotron site	APS
Beamline	19-ID
Temperature [K]	100
Detector technology	PIXEL
Collection date	2016-02-22
Detector	DECTRIS PILATUS3 6M
Wavelength(s)	0.97926
Spacegroup name	P 1 21 1
Unit cell lengths	58.020, 117.031, 64.444
Unit cell angles	90.00, 92.54, 90.00

Refinement procedure

Resolution	50.000 - 1.940
R-factor	0.1806
Rwork	0.180
R-free	0.22290
RMSD bond length	0.010
RMSD bond angle	1.374
Data reduction software	HKL-3000
Data scaling software	SCALEPACK
Phasing software	PHASER
Refinement software	REFMAC (5.8.0135)

Data quality characteristics

	Overall	Inner shell	Outer shell
Low resolution limit [Å]	50.000	50.000	1.970
High resolution limit [Å]	1.940	5.260	1.940
Rmerge	0.101	0.043	0.938
Rmeas	0.110	0.046	1.026
Rpim	0.042	0.018	0.410
Number of reflections	62638	3187	3111
<I/σ(I)>	4.8
Completeness [%]	98.9	98.5	99.4
Redundancy	6.6	6.7	6
CC(1/2)		0.999	0.690

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		291	20% PEG 3350, 0.2 M NH4SO4