6C4J
Ligand bound full length hUGDH with A104L substitution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | UDP-glucose 6-dehydrogenase | polymer | 494 | 55136.0 | 12 | UniProt (O60701) Pfam (PF03721) Pfam (PF00984) Pfam (PF03720) In PDB | Homo sapiens (Human) | UDPGDH |
| 2 | K, E, F, L, G... | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 12 | Chemie (NAD) | |||
| 3 | K, E, F, L, G... | URIDINE-5'-DIPHOSPHATE-GLUCOSE | non-polymer | 566.3 | 12 | Chemie (UPG) | |||
| 4 | K, L, G, A, B... | CHLORIDE ION | non-polymer | 35.5 | 13 | Chemie (CL) | |||
| 5 | D, E, K, F, G... | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 6 | D, E, K, F, L... | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 6 | Chemie (PGO) | |||
| 7 | water | water | 18.0 | 595 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 494 (UniProt: O60701)
| PDB | External Database | Details |
|---|---|---|
| Leu 104 | Ala 104 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 661632.2 | |
| Non-Polymers* | Number of molecules | 51 |
| Total formula weight | 16442.7 | |
| All* | Total formula weight | 678074.9 |
