5ZQU
Crystal structure of tetrameric RXRalpha-LBD complexed with partial agonist CBt-PMN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Retinoic acid receptor RXR-alpha | polymer | 243 | 27124.3 | 4 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| 2 | E, F, K, O, R... (A, B, C, D) | 1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)benzotriazole-5-carboxylic acid | non-polymer | 363.5 | 6 | Chemie (9HF) | |||
| 3 | G, H, I, J, L... (A, B, C, D) | BROMIDE ION | non-polymer | 79.9 | 11 | Chemie (BR) | |||
| 4 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 224 - 462 (UniProt: P19793)
| PDB | External Database | Details |
|---|---|---|
| Gly 220 | - | expression tag |
| Ser 221 | - | expression tag |
| Ser 222 | - | expression tag |
| His 223 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 108497.2 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3059.7 | |
| All* | Total formula weight | 111556.8 |
