5ZMC
Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | DNA (5'-D(P*CP*GP*GP*GP*GP*AP*CP*CP*CP*GP*GP*AP*AP*GP*GP*G)-3') | polymer | 16 | 5014.2 | 1 | Homo sapiens | ||
| 2 | B (D) | DNA (5'-D(P*GP*CP*CP*CP*TP*TP*CP*CP*GP*GP*GP*TP*CP*CP*CP*C)-3') | polymer | 16 | 4787.1 | 1 | Homo sapiens | ||
| 3 | C (B) | Protein C-ets-1 | polymer | 111 | 13114.9 | 1 | UniProt (P14921) Pfam (PF00178) | Homo sapiens (Human) | p54 |
| 4 | D (A) | Nuclear factor NF-kappa-B p100 subunit | polymer | 295 | 33166.0 | 1 | UniProt (Q00653) Pfam (PF00554) Pfam (PF16179) | Homo sapiens (Human) | DNA-binding factor KBF2,H2TF1,Lymphocyte translocation chromosome 10 protein,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2,Oncogene Lyt-10,Lyt10 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56082.2 | |
| All* | Total formula weight | 56082.2 |
