5ZG1
Crystal structure of the GluA2o LBD in complex with glutamate and Compound-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor 2 | polymer | 263 | 29337.8 | 2 | UniProt (P42262) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (Human) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | C, I (A, B) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 3 | D (A) | 9-(4-~{tert}-butylphenyl)-3,4-dihydropyrido[2,1-c][1,2,4]thiadiazine 2,2-dioxide | non-polymer | 316.4 | 1 | Chemie (9C0) | |||
| 4 | E, F, J, K (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | G, H, L, M, N... (A, B) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 6 | P, Q (A, B) | water | water | 18.0 | 562 | Chemie (HOH) |
Sequence modifications
A, B: 413 - 526 (UniProt: P42262)
A, B: 653 - 796 (UniProt: P42262)
| PDB | External Database | Details |
|---|---|---|
| Gly 411 | - | expression tag |
| Ser 412 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Lys 527 | - | linker |
| Gly 641 | - | linker |
| Thr 642 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58675.7 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1547.5 | |
| All* | Total formula weight | 60223.2 |
