5X07

Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J (D, A, G, J)	DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3')	polymer	16	4860.2	4		Homo sapiens
2	B, E, H, K (E, B, H, K)	DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3')	polymer	16	4932.3	4		Homo sapiens
3	C, F, I, L (F, C, I, L)	Hepatocyte nuclear factor 3-beta	polymer	104	12392.2	4	UniProt (Q9Y261) Pfam (PF00250)	Homo sapiens (Human)	HNF-3B,Forkhead box protein A2,Transcription factor 3B,TCF-3B

Sequence modifications

F, C, I, L: 157 - 258 (UniProt: Q9Y261)

PDB	External Database	Details
Gly 155	-	expression tag
Pro 156	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	88738.6
All*	Total formula weight	88738.6

*Water molecules are not included.