5X07

Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription
C	0043565	molecular_function	sequence-specific DNA binding
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0006355	biological_process	regulation of DNA-templated transcription
F	0043565	molecular_function	sequence-specific DNA binding
I	0003700	molecular_function	DNA-binding transcription factor activity
I	0006355	biological_process	regulation of DNA-templated transcription
I	0043565	molecular_function	sequence-specific DNA binding
L	0003700	molecular_function	DNA-binding transcription factor activity
L	0006355	biological_process	regulation of DNA-templated transcription
L	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PROSITE/UniProt

site_id	PS00657
Number of Residues	14
Details	FORK_HEAD_1 Fork head domain signature 1. KPPYSYisLitm.AI

Chain	Residue	Details
F	LYS159-ILE172

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site_id	PS00658
Number of Residues	7
Details	FORK_HEAD_2 Fork head domain signature 2. WQNSIRH

Chain	Residue	Details
F	TRP203-HIS209

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	372
Details	DNA_BIND: Fork-head => ECO:0000255|PROSITE-ProRule:PRU00089

Chain	Residue	Details
F	LYS159-GLN252
C	LYS159-GLN252
I	LYS159-GLN252
L	LYS159-GLN252

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P32182

Chain	Residue	Details
F	SER212
C	SER212
I	SER212
L	SER212

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