5UVV
BRD4 Bromodomain 2 with A-1457066
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 4 | polymer | 109 | 12806.9 | 2 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (Human) | Protein HUNK1 |
| 2 | C, D (A, B) | 7-(cyclopropylmethyl)-10-(ethylsulfonyl)-2-methyl-2,4,6,7-tetrahydro-3H-2,4,7-triazadibenzo[cd,f]azulen-3-one | non-polymer | 397.5 | 2 | Chemie (8NS) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A, B: 352 - 457 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 349 | - | expression tag |
| His 350 | - | expression tag |
| Met 351 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25613.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 795.0 | |
| All* | Total formula weight | 26408.8 |
