5UR7
Crystal structure of engineered CCL20 disulfide locked dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | C-C motif chemokine 20 | polymer | 70 | 8059.6 | 2 | UniProt (P78556) Pfam (PF00048) | Homo sapiens (Human) | Beta-chemokine exodus-1,CC chemokine LARC,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP-3-alpha,Small-inducible cytokine A20 |
| 2 | C, D, E, G, H (A, B) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 3 | F (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 70 (UniProt: P78556)
| PDB | External Database | Details |
|---|---|---|
| Cys 64 | Ser 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16119.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 355.3 | |
| All* | Total formula weight | 16474.6 |
