5T8D
Engineered variant of I-OnuI meganuclease targeting the HIV integrase gene; harbors 47 point mutations relative to wild-type I-OnuI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | I-OnuI_e-vHIVInt_v2 | polymer | 296 | 34426.8 | 1 | synthetic construct | ||
| 2 | B (B) | DNA (26-MER) | polymer | 26 | 8036.2 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (26-MER) | polymer | 26 | 7938.1 | 1 | synthetic construct | ||
| 4 | D, E, F (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 5 | G, H, I (A, B, C) | water | water | 18.0 | 259 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50401.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 120.2 | |
| All* | Total formula weight | 50521.3 |
