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5T8D

Engineered variant of I-OnuI meganuclease targeting the HIV integrase gene; harbors 47 point mutations relative to wild-type I-OnuI

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AI-OnuI_e-vHIVInt_v2polymer29634426.81synthetic construct
2BDNA (26-MER)polymer268036.21synthetic construct
3CDNA (26-MER)polymer267938.11synthetic construct
4ACALCIUM IONnon-polymer40.13Chemie (CA)
5waterwater18.0259Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight50401.1
Non-Polymers*Number of molecules3
Total formula weight120.2
All*Total formula weight50521.3
*Water molecules are not included.

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PDB entries from 2024-08-14

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