5T8D
Engineered variant of I-OnuI meganuclease targeting the HIV integrase gene; harbors 47 point mutations relative to wild-type I-OnuI
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004519 | molecular_function | endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | GLU22 |
| A | GLY177 |
| A | HOH566 |
| A | HOH619 |
| B | DA17 |
| C | DT15 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| B | DC16 |
| B | HOH145 |
| C | DA16 |
| A | ALA21 |
| A | GLU178 |
| A | HOH540 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | GLU22 |
| A | GLY177 |
| A | GLU178 |
| B | DC16 |
| B | DA17 |
| C | DT15 |
| C | DA16 |
