5SVS
Anomalous Mn2+ signal reveals a divalent cation-binding site in the head domain of the ATP-gated human P2X3 ion channel
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | P2X purinoceptor 3 | polymer | 363 | 40745.9 | 1 | UniProt (P56373) Pfam (PF00864) | Homo sapiens (Human) | P2X3,ATP receptor,Purinergic receptor |
| 2 | B, C, D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 3 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | F (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | G (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | I (A) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 6 - 364 (UniProt: P56373)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Arg 4 | - | expression tag |
| Ala 5 | - | expression tag |
| Pro 13 | Thr 13 | engineered mutation |
| Val 15 | Ser 15 | engineered mutation |
| Ile 16 | Val 16 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40745.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 967.2 | |
| All* | Total formula weight | 41713.1 |
