5NMV
Crystal structure of 2F22 Fab fragment against TFPI1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L | Fab light chain | polymer | 213 | 23242.8 | 1 | Mus | ||
2 | H | Fab heavy chain | polymer | 222 | 23814.7 | 1 | Mus | ||
3 | K | Tissue factor pathway inhibitor | polymer | 86 | 9797.9 | 1 | UniProt (P10646) Pfam (PF00014) In PDB | Homo sapiens (Human) | TFPI,Extrinsic pathway inhibitor,EPI,Lipoprotein-associated coagulation inhibitor,LACI |
4 | L, H | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
5 | water | water | 18.0 | 489 | Chemie (HOH) |
Sequence modifications
K: 1 - 79 (UniProt: P10646)
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Ser -5 | - | expression tag |
Ser -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Ser -1 | - | expression tag |
Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 56855.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 368.4 | |
All* | Total formula weight | 57223.8 |