Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5MZE

Crystal structure of mouse MTH1 with 8-oxo-dGTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D7,8-dihydro-8-oxoguanine triphosphatasepolymer17620101.74UniProt (P53368)
Pfam (PF00293)
In PDB
Mus musculus (House Mouse)2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1
2A, B, CCOPPER (II) IONnon-polymer63.54Chemie (CU)
3A, DDI(HYDROXYETHYL)ETHERnon-polymer106.12Chemie (PEG)
4A, B, C, D8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATEnon-polymer523.24Chemie (8DG)
5BGLYCEROLnon-polymer92.11Chemie (GOL)
6waterwater18.0408Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 156 (UniProt: P53368)
PDBExternal DatabaseDetails
Met -19-initiating methionine
Gly -18-expression tag
Ser -17-expression tag
Ser -16-expression tag
His -15-expression tag
His -14-expression tag
His -13-expression tag
His -12-expression tag
His -11-expression tag
His -10-expression tag
Ser -9-expression tag
Ser -8-expression tag
Gly -7-expression tag
Leu -6-expression tag
Val -5-expression tag
Pro -4-expression tag
Arg -3-expression tag
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight80406.6
Non-Polymers*Number of molecules11
Total formula weight2651.2
All*Total formula weight83057.9
*Water molecules are not included.

222624

PDB entries from 2024-07-17

PDB statisticsPDBj update infoContact PDBjnumon