5MWG
Crystal structure of the human BRPF1 bromodomain in complex with BZ091
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peregrin | polymer | 116 | 13703.7 | 2 | UniProt (P55201) Pfam (PF00439) In PDB | Homo sapiens (Human) | Bromodomain and PHD finger-containing protein 1,Protein Br140 |
| 2 | A, B | ~{N}-[1,4-dimethyl-2,3-bis(oxidanylidene)-7-piperidin-1-yl-quinoxalin-6-yl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide | non-polymer | 482.6 | 2 | Chemie (WGX) | |||
| 3 | A | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 4 | water | water | 18.0 | 447 | Chemie (HOH) |
Sequence modifications
A, B: 626 - 740 (UniProt: P55201)
| PDB | External Database | Details |
|---|---|---|
| Ser 625 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27407.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1027.2 | |
| All* | Total formula weight | 28434.6 |
