5MF0
Crystal structure of Smad4-MH1 bound to the GGCCG site.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | MH1 domain of human Smad4 | polymer | 135 | 15237.6 | 2 | UniProt (Q13485) Pfam (PF03165) | Homo sapiens (Human) | Mothers against DPP homolog 4,Deletion target in pancreatic carcinoma 4,SMAD family member 4,hSMAD4 |
| 2 | C, D (E, F) | DNA (5'-D(P*AP*CP*GP*GP*GP*CP*CP*GP*CP*GP*GP*CP*CP*CP*GP*T)-3') | polymer | 16 | 4901.2 | 2 | Homo sapiens | ||
| 3 | E, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F, H (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | I, J (B, E) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B: 10 - 140 (UniProt: Q13485)
| PDB | External Database | Details |
|---|---|---|
| Gly 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Met 8 | - | expression tag |
| Gly 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 40277.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 201.7 | |
| All* | Total formula weight | 40479.2 |
