5JBT
Mesotrypsin in complex with cleaved amyloid precursor like protein 2 inhibitor (APLP2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PRSS3 protein | polymer | 224 | 24257.5 | 1 | UniProt (Q8N2U3) Pfam (PF00089) UniProt (by SIFTS) (P35030) | Homo sapiens (Human) | |
| 2 | B (X) | Amyloid-like protein 2 | polymer | 14 | 1482.7 | 1 | UniProt (Q06481) | Homo sapiens (Human) | APLP-2,APPH,Amyloid protein homolog,CDEI box-binding protein,CDEBP |
| 3 | C (Y) | Amyloid-like protein 2 | polymer | 38 | 4423.1 | 1 | UniProt (Q06481) Pfam (PF00014) | Homo sapiens (Human) | APLP-2,APPH,Amyloid protein homolog,CDEI box-binding protein,CDEBP |
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E (Y) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | F, G, H (A, X, Y) | water | water | 18.0 | 259 | Chemie (HOH) |
Sequence modifications
A: 16 - 246 (UniProt: Q8N2U3)
| PDB | External Database | Details |
|---|---|---|
| Ala 195 | Ser 204 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 30163.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 136.1 | |
| All* | Total formula weight | 30299.4 |
