5GTM

Modified human MxA, nucleotide-free form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Interferon-induced GTP-binding protein Mx1	polymer	601	68429.7	2	UniProt (P20591) Pfam (PF00350) Pfam (PF01031) Pfam (PF02212) In PDB	Homo sapiens (Human)	Interferon-induced protein p78,IFI-78K,Interferon-regulated resistance GTP-binding protein MxA,Myxoma resistance protein 1,Myxovirus resistance protein 1
2		water	water		18.0	3	Chemie (HOH)

Sequence modifications

A, B: 33 - 662 (UniProt: P20591)

PDB	External Database	Details
Ser 376	Ile 376	engineered mutation
Ile 379	Val 379	variant
Ala 440	Tyr 440	engineered mutation
Ala 441	Arg 441	engineered mutation
Ala 442	Gly 442	engineered mutation
Ala 443	Arg 443	engineered mutation
Asp 527	Met 527	engineered mutation
-	Cys 533	deletion
-	Gln 534	deletion
-	Asp 535	deletion
-	Gln 536	deletion
-	Val 537	deletion
-	Tyr 538	deletion
-	Arg 539	deletion
-	Gly 540	deletion
-	Ala 541	deletion
-	Leu 542	deletion
-	Gln 543	deletion
-	Lys 544	deletion
-	Val 545	deletion
-	Arg 546	deletion
-	Glu 547	deletion
-	Lys 548	deletion
-	Glu 549	deletion
-	Leu 550	deletion
-	Glu 551	deletion
-	Glu 552	deletion
-	Glu 553	deletion
-	Lys 554	deletion
-	Lys 555	deletion
-	Lys 556	deletion
-	Lys 557	deletion
-	Ser 558	deletion
-	Trp 559	deletion
-	Asp 560	deletion
-	Phe 561	deletion
Ser 614	Lys 614	engineered mutation
Ser 617	Leu 617	engineered mutation
Ser 620	Leu 620	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	136859.4
All*	Total formula weight	136859.4

*Water molecules are not included.