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5GTM

Modified human MxA, nucleotide-free form

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0005829cellular_componentcytosol
A0005874cellular_componentmicrotubule
A0006915biological_processapoptotic process
A0006952biological_processdefense response
A0007165biological_processsignal transduction
A0008017molecular_functionmicrotubule binding
A0009615biological_processresponse to virus
A0016020cellular_componentmembrane
A0031965cellular_componentnuclear membrane
A0034340biological_processresponse to type I interferon
A0042802molecular_functionidentical protein binding
A0045071biological_processnegative regulation of viral genome replication
A0045087biological_processinnate immune response
A0048471cellular_componentperinuclear region of cytoplasm
A0051607biological_processdefense response to virus
A0070106biological_processinterleukin-27-mediated signaling pathway
A0140374biological_processantiviral innate immune response
B0003924molecular_functionGTPase activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005783cellular_componentendoplasmic reticulum
B0005789cellular_componentendoplasmic reticulum membrane
B0005829cellular_componentcytosol
B0005874cellular_componentmicrotubule
B0006915biological_processapoptotic process
B0006952biological_processdefense response
B0007165biological_processsignal transduction
B0008017molecular_functionmicrotubule binding
B0009615biological_processresponse to virus
B0016020cellular_componentmembrane
B0031965cellular_componentnuclear membrane
B0034340biological_processresponse to type I interferon
B0042802molecular_functionidentical protein binding
B0045071biological_processnegative regulation of viral genome replication
B0045087biological_processinnate immune response
B0048471cellular_componentperinuclear region of cytoplasm
B0051607biological_processdefense response to virus
B0070106biological_processinterleukin-27-mediated signaling pathway
B0140374biological_processantiviral innate immune response
Functional Information from PROSITE/UniProt
site_idPS00410
Number of Residues10
DetailsG_DYNAMIN_1 Dynamin-type guanine nucleotide-binding (G) domain signature. LPRGSGIVTR
ChainResidueDetails
ALEU95-ARG104

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000255
ChainResidueDetails
AGLY77
AASP178
ATHR247
BGLY77
BASP178
BTHR247

220472

PDB entries from 2024-05-29

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