5FPB
Crystal structure of human KDM4D in complex with 2-1H-pyrazol-4-yloxy- 3H,4H-pyrido-3,4-d-pyrimidin-4-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | LYSINE-SPECIFIC DEMETHYLASE 4D | polymer | 334 | 38534.6 | 1 | UniProt (Q6B0I6) Pfam (PF02375) Pfam (PF02373) | HOMO SAPIENS (HUMAN) | JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3D, JU MONJI DOMAIN-CONTAINING PROTEIN 2D, HUMAN LYSINE-SPECIFIC DEMETHYL ASE 4D, JMJD2D |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 4 | D (A) | 2-(1H-pyrazol-4-yloxy)-3H-pyrido[3,4-d]pyrimidin-4-one | non-polymer | 229.2 | 1 | Chemie (HA6) | |||
| 5 | E, F, G, H, I... (A) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 6 | L (A) | water | water | 18.0 | 472 | Chemie (HOH) |
Sequence modifications
A: 11 - 341 (UniProt: Q6B0I6)
| PDB | External Database | Details |
|---|---|---|
| Gly 8 | - | expression tag |
| His 9 | - | expression tag |
| Met 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38534.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1026.0 | |
| All* | Total formula weight | 39560.6 |
