5F8A
Crystal structure of the ternary EcoRV-DNA-Lu complex with uncleaved DNA substrate. Lanthanide binding to EcoRV-DNA complex inhibits cleavage.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, D | DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*T)-3') | polymer | 12 | 3660.4 | 2 | synthetic construct | ||
2 | A, B | Type-2 restriction enzyme EcoRV | polymer | 244 | 28559.2 | 2 | UniProt (P04390) Pfam (PF09233) In PDB | Escherichia coli | R.EcoRV,Endonuclease EcoRV,Type II restriction enzyme EcoRV |
3 | A, B | LUTETIUM (III) ION | non-polymer | 175.0 | 2 | Chemie (LU) | |||
4 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
5 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
6 | water | water | 18.0 | 301 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 64439.2 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 520.1 | |
All* | Total formula weight | 64959.2 |